Tildren® is a drug that has been available in Europe for many years to treat navicular disease and has recently become available in the United States to veterinarians who go through special licensure. It is similar to drugs used to treat osteoporosis in people. The activity of the cells that cause the destructive changes we see on X-rays with navicular disease is suppressed. Apparently the activity of these cells is very painful and by reducing their activity, many horses become much more comfortable. There are many different treatment protocols being utilized with Tildren but most involve placement of an iv catheter and administration of a large amount of the drug as an iv drip for about an hour. Generally in 2-4 weeks the benefits are beginning to be realized and the effect lasts for approximately six months. Horses may remain sound longer by giving monthly boosters. In addition to navicular disease, many veterinarians use Tildren to treat horses with hock pain. Many lameness diagnosticians feel that Tildren has been the first major breakthrough in the treatment of navicular disease in horses.
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